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文章摘要
李亚君 唐娜娜 陈抒鹏 李同心.基于中医学治未病思想构建冠状动脉粥样硬化性心脏病风险评估预警系统的研究[J].江西中医药大学学报,2026,38(1):37-41.
基于中医学治未病思想构建冠状动脉粥样硬化性心脏病风险评估预警系统的研究
Research on the Construction of a Risk Assessment and Early Warning System for Coronary Atherosclerotic Heart Disease Based on the Preventive Treatment Concept of Traditional Chinese Medicine
  
DOI:10.20140/j.2095-7785.2026.01.09
中文关键词: 冠状动脉粥样硬化性心脏病;治未病;预警模型;风险评估
英文关键词: Coronary Atherosclerotic Heart Disease; Prevention Before Illness; Early Warning Model; Risk Assessment
基金项目:全国名老中医药专家传承工作室建设项目(国中药人教函[2022]75 号);江西省卫健委科技计划项目(202310692);江西省教育厅科技计 划项目(GJJ211216)
作者单位
李亚君1 唐娜娜2 陈抒鹏1 李同心1 1 . 江西中医药大学 南昌 330004;2 . 江西中医药大学 附属医院 南昌 330006 
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中文摘要:
      目的:分析冠状动脉粥样硬化性心脏病(CAHD)首次发病的独立危险因素,构建及验证风险评估预警系统。方法: 将2 532 例江西中医药大学附属医院2023 年1 月—2024 年5 月门诊及住院患者的病史资料纳入原始数据库,利用SPSS 软 件执行单因素与多因素Logistic 回归分析,筛选出导致CAHD 首次发病的独立危险因素,构建风险评估预警模型,并通过 F1-score 对模型进行验证。结果:分析发现,年龄≥ 60 岁、体重指数≥ 24 kg/m2、既往高血压病病史、既往糖尿病病史和既 往高脂血症病史均为CAHD 首次发病的独立危险因素。将其作为模型的最终预测因子,构建风险预估模型。通过F1-score 进行模型验证,在测试集模型中综合平均值为0.98,在验证集模型中综合平均值为0.97,表明模型的性能好,具备较强的实 际应用能力和较好的泛化性。结论:本研究明确了年龄≥ 60 岁、体重指数≥ 24 kg/m2、既往高血压病病史、既往糖尿病病史 和既往高脂血症病史均为CAHD 首次发病的独立危险因素,建立了以中医治未病理论为基础的CAHD 临床风险预测模型, 提出了不同风险等级CAHD 患者实施个体化的中医防治策略。
英文摘要:
      Objective: To analyze the independent risk factors for the first onset of coronary atherosclerotic heart disease and to construct and validate a risk assessment and warning system. Methods: The medical history data of 2532 patients from the outpatient and inpatient departments of Jiangxi University of Traditional Chinese Medicine Affiliated Hospital from January 2023 to May 2024 were included in the original database, and the independent risk factors for the first onset of coronary atherosclerotic heart disease were screened out by using the single-factor and multi-factor Logistic regression analysis in SPSS software. The risk assessment and warning model was constructed based on the final predictive factors, and the model was validated by F1-score. Results: The analysis found that age ≥ 60 years, body mass index (BMI)≥24 kg/m2, a history of hypertension, a history of diabetes, and a history of hyperlipidemia were independent risk factors for the first onset of coronary atherosclerotic heart disease. These factors were used as the final predictive factors to construct the risk prediction model. The model was validated by F1-score, with an average value of 0.98 in the test set model and 0.97 in the validation set, indicating that the model has good performance and strong practical application ability and good generalization. Conclusion: This study clarified that age ≥ 60 years, BMI ≥ 24 kg/m2, a history of hypertension, a history of diabetes, and a history of hyperlipidemia are independent risk factors for the first onset of coronary atherosclerotic heart disease. A clinical risk prediction model for coronary atherosclerotic heart disease based on traditional Chinese medicine preventive medicine theory was established. Individualized TCM prevention and treatment strategies were proposed for patients with different risk levels of coronary atherosclerotic heart disease.
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