| 刘云 喻影媛 杨晓娟 胡佳 张平 何凌 钟超.润肠丸贴敷联合复方聚乙二醇电解质散对改善血虚型便秘患者肠道准备质量的
临床研究[J].江西中医药大学学报,2025,37(5):36-39. |
| 润肠丸贴敷联合复方聚乙二醇电解质散对改善血虚型便秘患者肠道准备质量的
临床研究 |
| Clinical Study on Runchang Pill Application Combined with Compound Polyethylene Glycol Electrolyte Powder in Improving Bowel Preparation Quality of Patients with Blood DeficiencyType Constipation |
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| DOI：10.20140/j.2095-7785.2025.25.11 |
| 中文关键词: 润肠丸；血虚证；便秘；结肠镜检查；肠道准备；复方聚乙二醇电解质散；穴位贴敷 |
| 英文关键词: Runchang Pill; Blood Deficiency; Constipation; Colonoscopy Preparation; Compound Polyethylene Glycol Electrolyte Powder;
Acupoint Application |
| 基金项目:江西省中医药管理局科技计划项目（2022B132） |
| 作者 | 单位 | | 刘云 喻影媛 杨晓娟 胡佳 张平 何凌 钟超 | 江西中医药大学附属医院 南昌 330006 |
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| 中文摘要: |
| 目的：研究润肠丸中药贴敷联合复方聚乙二醇电解质散对结肠镜检查前肠道准备质量的改善情况，优化血虚型便秘患
者肠道准备用药方案。方法：选择行结肠镜检查的血虚型便秘患者 200 例，随机分配到对照组（n=100）及观察组（n=100）。
对照组于检查当天早晨 5 ：00—7 ：00 口服复方聚乙二醇电解质散 2 000 mL ；观察组于检查前 1 天 8 ：00—20 ：00（间隔 12 h）
取神阙和天枢穴，将配制好的润肠丸穴位贴行中药贴敷，共贴敷 2 次，而后在检查当天 5 ：00—7 ：00 口服与对照组相同剂量的
复方聚乙二醇电解质散。检查期间观察患者肠道清洁度及肠腔内气泡等结局指标。结果：观察组较对照组肠道清洁度明显提高，
肠腔内气泡明显减少，总体不良反应评分降低，2 组肠道清洁度总体均数、肠腔内气泡评分总体均数、2 组总体不良反应评分
均存在统计学差异；2 组腺瘤检出率，尤其是直径 <0.5 cm 腺瘤检出率观察组高于对照组，差异有统计学意义。结论：润肠丸贴
敷联合复方聚乙二醇电解质散可明显提高血虚型便秘患者肠道准备质量，减轻腹痛腹胀等不良反应，具有临床应用价值。 |
| 英文摘要: |
| Objective: To study the effect of Runchang Pill combined with compound polyethylene glycol electrolyte powder on intestinal
preparation before colonoscopy, and optimize the intestinal preparation medication scheme for patients with blood deficiency constipation.
Methods: A total of 200 patients undergoing colonoscopy were randomly assigned to control group (n=100) and observation group
(n=100). The control group took 2 000 mL of compound polyethylene glycol electrolyte powder orally from 5 am to 7 am one day before the
examination, the observation group was applied at 8 am and 20 pm (12 hours interval) at Shenque point and Tianshu point, and the prepared
acupoints were applied for two times, and then the same dose of compound polyethylene glycol electrolyte powder was taken orally from
5 am to 7 am on the examination day. The outcome indexes such as intestinal cleanliness and intestinal bubble were observed during the
examination. Results: Compared with the control group, the intestinal cleanliness was significantly improved, the intestinal bubble was
significantly reduced, and the overall adverse reaction score was decreased. The overall mean of intestinal cleanliness, the overall mean
of intestinal bubble score and the overall adverse reaction score were statistically different between the two groups. The detection rate of
adenomas, especially those with diameter < 0.5 cm, in the observation group was higher than that in the control group, and the difference was
statistically significant. Conclusion: The combination of Runchang Pill and compound polyethylene glycol electrolyte powder can obviously
improve the quality of intestinal preparation and alleviate the adverse reactions such as abdominal pain and distension in patients with blood
deficiency constipation, and has clinical application value. |
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