文章摘要
| .江西省老年髓系恶性血液肿瘤证型分布规律回顾性
分析[J].江西中医药大学学报,2024,36(2):51-54,87. |
| 江西省老年髓系恶性血液肿瘤证型分布规律回顾性
分析 |
| Retrospective Analysis of the Distribution Pattern of Senile Myeloid Malignant Hematologic Tumors in Jiangxi Province |
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| DOI：10.20140/j.2095-7785.2024.02.14 |
| 中文关键词: 江西省；急性髓系白血病；骨髓增生异常综合征；中医证型；回顾性分析 |
| 英文关键词: Jiangxi Province; Acute Myeloid Leukemia; Myelodysplastic Syndrome; TCM Syndrome Type; Retrospective Analysis |
| 基金项目:江西省中医药重点临床研究基地项目（赣中医药科教字［2021］3 号）；江西省中医药中青年骨干人才（第一批）培养计划项目（赣中医
药科教字［2021］2 号） |
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| 中文摘要: |
| 目的：探讨江西省老年髓系恶性血液肿瘤常见的中医证型分布规律，以便更好地指导临床诊断和治疗。方法：将收
集的 120 例居住生活在江西省内的老年髓系恶性血液肿瘤患者的中医四诊资料，经副主任中医师及以上职称的医师复核，建
立病历资料数据库，采用 SPPS 26.0 软件对患者的居住地、年龄、性别、常见症状、舌象、脉象、证型、外周血象、骨髓增生情况、
病程等进行统计分析。结果：（1）120 例患者均来自江西省内各地市，其中男性 71 例（59.17%），女性 49 例（40.83%），男
性发病率高于女性，平均年龄（70.36±6.80）岁。（2）脾虚痰湿证 46 例，气血两虚证 26 例，气阴两虚证 24 例，瘀毒内结证
24 例，脾虚痰湿证所占比例最高（38.33%）。（3）中医证型与白细胞（WBC）计数、血小板（PLT）计数比较差异均有统计
学意义（P<0.05），与血红蛋白（Hb）计数比较差异无统计学意义（P>0.05）。（4）中医证型与骨髓增生情况比较差异无统
计学意义（P>0.05）。（5）中医证型与病程之间的关系比较具有显著性统计学意义（P<0.01）。结论：（1）江西省老年髓系
恶性血液肿瘤发病率男性高于女性，平均年龄（70.36±6.80）岁。（2）常见的中医证型以脾虚痰湿证较多，其次为气血两虚证、
气阴两虚证、瘀毒内结证。（3）WBC 低于正常值以气血两虚证多见，WBC 高于正常值以瘀毒内结证较多见；PLT 低于正常
值以气阴两虚证多见。（4）病程长者多见于脾虚痰湿证，病程较短者多见于瘀毒内结证。 |
| 英文摘要: |
| Objective: To explore the distribution pattern of TCM syndromes in elderly myeloid malignant blood tumors in Jiangxi province,
in order to better guide clinical diagnosis and treatment. Methods: The collected TCM data of 120 elderly patients with myeloid malignant
blood tumor living in Jiangxi province were reviewed by physicians with the title of deputy chief TCM physician or above to establish a
database of medical records SPPS 26.0 software was used for statistical analysis of the patient's residence, age, sex, common symptoms,
tongue, pulse, syndrome type, peripheral blood, myelodysplasia and disease course. Results: (1) The 120 patients were all from various cities
in Jiangxi province, including 71 males (59.17%) and 49 females (40.83%). The incidence rate of males was higher than that of females, with
an average age of (70.36±6.80) years. (2) There were 46 cases of spleen deficiency and phlegm-dampness syndrome, 26 cases of deficiency
of Qi and blood, 24 cases of deficiency of Qi and Yin, 24 cases of stagnation and toxin, the highest proportion of spleen deficiency and
phlegm-dampness syndrome (38.33%). (3) TCM syndrome type had statistical significance with WBC count and platelet count (P<0.05), but
had no statistical significance with hemoglobin count (P>0.05). (4) There was no significant difference between TCM syndrome type and bone
marrow hyperplasia (P>0.05). (5) The relationship between TCM syndrome type and course of disease was statistically significant (P<0.01).
Conclusion: (1) The incidence of myeloid malignant blood tumors in the elderly in Jiangxi province was higher in males than in females,
with an average age of (70.36±6.80) years. (2) The most common TCM syndromes are spleen deficiency and phlegm-dampness syndrome,
followed by deficiency of Qi and blood, deficiency of Qi and Yin, stasis and toxin. (3) Leucocyte lower than normal was more common in
syndrome of deficiency of Qi and blood, while high leucocyte was more common in syndrome of stasis and toxin. Platelet lower than normal
is more common in Qi and Yin deficiency syndrome. (4) The longer course of the disease is more common in spleen deficiency phlegmdampness syndrome, the shorter course of the disease is more common in stasis and toxin syndrome |
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